### README - Blood-Cell Consortium (BCX) ### June 29 2016 This readme describes the summary ExomeChip association data reported in three articles published by the Blood-Cell Consortium in the July 2016 issue of the : American Journal of Human Genetics 1. Large-scale exome-wide association analysis identifies loci for white blood cell traits and pleiotropy with immune-mediated diseases (PMID: 27346689) 2. Platelet-related variants identified by ExomeChip meta-analysis in 157,293 individuals (PMID: 27346686) 3. Exome genotyping identifies pleiotropic variants associated with red blood cell traits (PMID: 27346685) Ancestry groups are: African Ancestry (AA) European Ancestry (EA) Combined all ancestries including Hispanic/Latino ancestry, East-Asian ancestry, South-Asian ancestry in addition to AA and EA (ALL) Columns in the files are: 1. CHR : chromosome 2. POS : basepair position in HG19 3. SNPNAME : RSid 4. REF : reference allele 5. ALT : effect allele 6. AFR_MAF or EUR_MAF or GMAF : minor allele frequency in 1KG (1000 Genomes project) 7. ExAC_AFR_MAF or ExAC_NFE_MAF or ExAC_MAF : minor allele frequency in ExAC (Exome Aggregation Consortium) 8. beta : effect size given for the ALT (effect) allele 9. se : standard error of beta 10. Pvalue : association p-value with blood-cell traits