HumanGen logo

Laboratory of Guillaume Lettre

Montreal Heart Institute | Université de Montréal

Université de Montréal Montréal Heart Institute
Home Opportunities



M.Sc./Ph.D/PostDoc positions available

The group of Dr. Lettre is working on understanding complex traits and common diseases in humans. We aim to identify genetic variation that influences cardiovascular and haematological disease risk using NGS techniques (RNA-seq, ATAC-seq, Chip-seq), genome editing technology (CRISPR-cas9), chromosome conformation capture techniques (Hi-C), together with state-of-the-art computational and bioinformatics approaches.

Postdoctoral position in Cardiovascular Genetics and Bioinformatics

Applications are invited for the position of Postdoctoral Fellow in Cardiovascular Genetics and Bioinformatics in the group of Guillaume Lettre at the Montreal Heart Institute (affiliated with the Université de Montréal).

We seek a highly motivated, proactive individual who will benefit from the exceptional research environment for human genetics, bioinformatics, functional genomics, and big data -omics found at the Montreal Heart Institute. You will play a key role leading genetic and bioinformatic analyses of large next-generation sequencing (NGS) datasets (including DNA whole-genome sequence, RNA-seq, ATAC-seq, ChIP-seq, Hi-C conformation experiments) to define new risk factors of cardiovascular diseases. You will have access to data from multiple patient cohorts, including >20,000 participants from the Montreal Heart Institue biobank. You will then build precision medicine models to predict cardiovascular disease outcomes in these populations.

You will have a PhD in bioinformatics, statistical genetics, statistics, mathematics, computer science or a related discipline together with experience of human genetics and/or functional genomic analysis and experience of, and demonstrated competence in, scientific computing using at least one statistical programme (e.g. R) and one programming language. Some knowledge of machine-learning methodologies and high-performance computing are also valuable assets. You will also have excellent analytical and quantitative skills and the ability to work in a team and a good publication record.

If interested, please submit your current curriculum vitae, names and email addresses of three referees, and a brief statement of interest to Guillaume Lettre (guillaume.lettre at

Last Updated on Thursday, 05 October 2017 13:13